89-7828-94 Recombinant Cavia porcellus CTLA-4/CD152 Protein (His Tag) 50ug PKSQ050093
[Elabscience]
特徴
- 背景：Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4.
仕様
- サイズ：50ug
- 種由来：Cavia porcellus
- 発現宿主：P.Pichia
- 純度：> 90% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：H0VUB1
- タグ種類：C-His
- アミノ酸配列：Ala37-Asp161
- 遺伝子構造：Recombinant Cavia porcellus CD152 is produced by our Yeast expression system and the target gene encoding Ala37-Asp161 is expressed with a 6His tag at the C-terminus.
- 活性：Immobilized Mouse B7-1-Fc(Cat: PKSM041366) at 1μg/ml(100 μl/well) can bind Cavia porcellus CTLA-4-His. The ED50 of Cavia porcellus CTLA-4-His is 0.17ug/ml .
- 別名（遺伝子名）：Cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4; CTLA-4; CD152; CTLA4
- 分子量：14.1 kDa
- 組成：Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
- 保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229839-Elabscience-PKSQ050093.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
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89-7828-93
Recombinant Cavia porcellus CTLA-4/CD152 Protein (His Tag) 10ug
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89-7828-94
Recombinant Cavia porcellus CTLA-4/CD152 Protein (His Tag) 50ug
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