89-7828-79 Recombinant Schistosoma Japonicum GST 26 Protein 10ug PKSQ050086
[Elabscience]
特徴
- 背景：Glutathione S-transferases (GSTs), previously known as ligandins, comprise a family of eukaryotic and prokaryotic phase II metabolic isozymes best known for their ability to catalyze the conjugation of the reduced form of glutathione (GSH) to xenobiotic substrates for the purpose of detoxification. The GST family consists of three superfamilies: the cytosolic, mitochondrial, and microsomal (MAPEG) proteins. GST isoenzymes appear to play a central role in the parasite detoxification system. Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut. The activity of GSTs is dependent upon a steady supply of GSH from the synthetic enzymes gamma-glutamylcysteine synthetase and glutathione synthetase, as well as the action of specific transporters to remove conjugates of GSH from the cell. The primary role of GSTs is to detoxify xenobiotics by catalyzing the nucleophilic attack by GSH on electrophilic carbon, sulfur, or nitrogen atoms of said nonpolar xenobiotic substrates, thereby preventing their interaction with crucial cellular proteins and nucleic acids.
仕様
- サイズ：10ug
- 種由来：Schistosoma Japonicum
- 発現宿主：E.coli
- 純度：> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：P08515
- アミノ酸配列：Met1-Lys218
- 遺伝子構造：Recombinant Schistosoma Japonicum GST 26 is produced by our E.coli expression system and the target gene encoding Met1-Lys218 is expressed.
- 別名（遺伝子名）：Glutathione S-transferase class-mu 26 kDa isozyme; GST 26; Sj26 antigen; SjGST
- 分子量：25.7 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229832-Elabscience-PKSQ050086.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7828-79
Recombinant Schistosoma Japonicum GST 26 Protein 10ug
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89-7828-80
Recombinant Schistosoma Japonicum GST 26 Protein 50ug
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