89-7828-55 Recombinant Rhesus macaque ICOS/AILIM/CD278 Protein (Fc Tag) 10ug PKSQ050074
[Elabscience]
特徴
- 背景：Inducible T-cell costimulator, also known as activation-inducible lymphocyte immunomediatory molecule, CD278, AILIM, CVID1 and ICOS, belongs to the CD28 and CTLA4 cell surface receptor family.. ICOS contains one Ig-like V-type domain and exsits as a homodimer with disulfide-linked. ICOS is highly expressed on tonsillar T-cellsand can be induced by PMA and ionomycin, ICOS plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. Defects in ICOS are the cause of immunodeficiency common variable type 1, which is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antige.
仕様
- サイズ：10ug
- 種由来：Rhesus macaque
- 発現宿主：Human Cells
- 純度：> 90% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：H9Z062
- タグ種類：C-Fc
- アミノ酸配列：Gly20-Lys140
- 遺伝子構造：Recombinant Rhesus macaque ICOS is produced by our Mammalian expression system and the target gene encoding Gly20-Lys140 is expressed with a Fc tag at the C-terminus.
- 別名（遺伝子名）：Inducible T-cell costimulator;activation-inducible lymphocyte immunomediatory molecule; CD278; AILIM; CVID1;ICOS
- 分子量：40.8 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS,pH 7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229820-Elabscience-PKSQ050074.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7828-56
Recombinant Rhesus macaque ICOS/AILIM/CD278 Protein (Fc Tag) 50ug
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89-7828-55
Recombinant Rhesus macaque ICOS/AILIM/CD278 Protein (Fc Tag) 10ug
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