89-7828-12 Recombinant Cynomolgus B7-H3/CD276 Protein (His Tag) 50ug PKSQ050052
[Elabscience]
特徴
- 背景：CD276, also known as B7-H3, is a member of the B7 superfamily with signature IgV and IgG regions in extracellular domains. It is a type I transmembrane protein and shares 20–27% amino acid identity with other B7 family members. B7-H3 is involved in the activation of T lymphocytes, and regulates murine bone formation. It is also reported that B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is expressed on T-cells, natural killer cells, and antigen presenting cells, as well as some non-immune cells, such as osteoblasts, fibroblasts, fibroblast-like synoviocytes and epithelial cells. High expression of B7-H3 in tumor vasculature also correlates with poor survival in patients, suggesting that it may play a role in tumor cell migration.
仕様
- サイズ：50ug
- 種由来：Cynomolgus
- 発現宿主：Human Cells
- 純度：> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：XP_015308534
- タグ種類：C-His
- アミノ酸配列：Leu29-Glu465
- 遺伝子構造：Recombinant Cynomolgus CD276 is produced by our Mammalian expression system and the target gene encoding Leu29-Glu465 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：CD276 antigen; CD276; B7 homolog 3; B7-H3;CD276
- 分子量：47.9 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS,pH 7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229798-Elabscience-PKSQ050052.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7828-12
Recombinant Cynomolgus B7-H3/CD276 Protein (His Tag) 50ug
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89-7828-11
Recombinant Cynomolgus B7-H3/CD276 Protein (His Tag) 10ug
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