89-7827-91 Recombinant Cynomolgus CTLA-4/CD152 Protein (Fc Tag) 50ug PKSQ050042
[Elabscience]
特徴
- 背景：Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T Cells and may play an important role in their functions. Tcell activation through the Tcell receptor and CD28 leads to increased expression of CTLA4.
仕様
- サイズ：50ug
- 種由来：Cynomolgus
- 発現宿主：Human Cells
- 純度：> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：G7PL88
- タグ種類：C-Fc
- アミノ酸配列：Ala37-Ser160
- 遺伝子構造：Recombinant Cynomolgus CTLA-4 is produced by our Mammalian expression system and the target gene encoding Ala37-Ser160 is expressed with a Fc tag at the C-terminus.
- 別名（遺伝子名）：Cytotoxic T-lymphocyte protein 4; Cytotoxic T-lymphocyte-associated antigen 4; CTLA-4; CD152; CTLA4
- 分子量：40.2 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 50 mM Tris, 100 mM Glycine, pH 7.5.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229788-Elabscience-PKSQ050042.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7827-90
Recombinant Cynomolgus CTLA-4/CD152 Protein (Fc Tag) 10ug
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89-7827-91
Recombinant Cynomolgus CTLA-4/CD152 Protein (Fc Tag) 50ug
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