89-7827-13 Recombinant Mouse TRAIL R2/TNFRSF10B Protein (AVI & His Tag) 100ug PKSM041369
[Elabscience]
特徴
- 背景：Mouse tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) is a member of the TNFR family which contains 1 death domain and 3 TNFR-Cys repeats. TNFRSF10B exhibits high structural and functional homology to TRAIL-R1 (DR-4). TNFRSF10B is highly expressed in heart, lung, lymphocytes, spleen and kidney. In addition, it is regulated by the tumor suppressor p53. TNFRSF10B is the receptor for the cytotoxic ligand TNFSF10/TRAIL. It promotes the activation of NF-kappa-B and is essential for ER stress-induced apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases mediating apoptosis.
仕様
- サイズ：100ug
- 種由来：Mouse
- 発現宿主：Human Cells
- 純度：> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：Q9QZM4
- タグ種類：C-Avi-His
- アミノ酸配列：Asn53-Ser177
- 遺伝子構造：Biotinylated Recombinant Mouse TRAILR2 is produced by our Mammalian expression system and the target gene encoding Asn53-Ser177 is expressed with a Avi-6Histag at the C-terminus.
- 別名（遺伝子名）：Tumor Necrosis Factor Receptor Superfamily Member 10B; Death Receptor 5; TNF-Related Apoptosis-Inducing Ligand Receptor 2; TRAIL Receptor 2; TRAIL-R2; CD262; TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9
- 分子量：16.4 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229751-Elabscience-PKSM041369.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7827-13
Recombinant Mouse TRAIL R2/TNFRSF10B Protein (AVI & His Tag) 100ug
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89-7827-12
Recombinant Mouse TRAIL R2/TNFRSF10B Protein (AVI & His Tag) 20ug
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