特徴
- 背景:Alpha-N-acetylgalactosaminide alpha -2,6-sialyltransferase 2, is a type?II membrane protein localized in the Golgi network and catalyzes 2,6-sialylation of the Tn antigen. Sialyl-Tn antigen is highly expressed in several human carcinomas and is associated with carcinoma aggressiveness and poor prognosis.?it has been reported that disregulation of this gene is involved in the pathogenesis of IgA nephropathy, a common kidney disease that occurs when antibody IgA accumulates in kidneys (4). The enzyme may also be used to synthesize a cancer vaccine.
仕様
- サイズ:10ug
- 種由来:Mouse
- 発現宿主:Human Cells
- 純度:> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per μg as determined by the LAL method.
- アクセッションNo.:P70277
- タグ種類:C-His
- アミノ酸配列:Ser28-Arg373
- 遺伝子構造:Recombinant Mouse ST6GALNAC2 is produced by our Mammalian expression system and the target gene encoding Ser28-Arg373 is expressed with a 6His tag at the C-terminus.
- 別名(遺伝子名):Gal-beta-1;3-GalNAc alpha-2;6-sialyltransferase;GalNAc alpha-2;6-sialyltransferase II;ST6GalNAc II;Sialyltransferase 7B;SIAT7-B;II;Siat7;Siat7b;ST6GalNAc
- 分子量:40.4 kDa
- 組成:Supplied as a 0.2 μm filtered solution of 50mMTris,150mMNaCl,pH7.5.
- 保存条件:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-229743-Elabscience-PKSM041361.pdf
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7826-95
Recombinant Mouse ST6GALNAC2 Protein (His Tag) 10ug
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89-7826-96
Recombinant Mouse ST6GALNAC2 Protein (His Tag) 50ug
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