89-7826-65 Recombinant Mouse Complement Factor H/CFH Protein (His Tag) 10ug PKSM041346
[Elabscience]
特徴
- 背景：Complement factor H(CFH) is a 155 kDa glycoprotein that functions as a cofactor in the inactivation of C3b by factor I. It also increases the rate of dissociation of the C3bBb complex (C3 convertase) and the (C3b)NBB complex (C5 convertase) in the alternative complement pathway. CFH expressed by the liver and secreted in plasma. This recombinant protein corresponds to SCR15-20 which encompass the primary binding sites for heparin and C3b as well as for the peptide hormone adrenomedullin. Within SCR15-20, mouse Factor H shares 60% and 80% amino acid sequence identity with human and rat Factor H, respectively. Dozens of mutations clustered in SCR15-20 are associated with atypical hemolytic uremic syndrome, a disorder characterized by anemia, thrombocytopenia, and renal failure.
仕様
- サイズ：10ug
- 種由来：Mouse
- 発現宿主：Human Cells
- 純度：> 90% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：E9Q8I0
- タグ種類：C-His
- アミノ酸配列：Ser875-Val1252
- 遺伝子構造：Recombinant Mouse Complement factor H is produced by our Mammalian expression system and the target gene encoding Ser875-Val1252 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：Complement factor H;Protein beta-1-H;CFH; beta-1-H-globulin
- 分子量：43.4 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,150mM NaCl,pH8.0.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229728-Elabscience-PKSM041346.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7826-65
Recombinant Mouse Complement Factor H/CFH Protein (His Tag) 10ug
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89-7826-66
Recombinant Mouse Complement Factor H/CFH Protein (His Tag) 50ug
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