89-7826-52 Recombinant Mouse EpCAM/TROP-1 Protein (Fc Tag)(Active) 50ug PKSM041339
[Elabscience]
特徴
- 背景：ROR1，also known as Neurotrophic tyrosine kinase, receptor-related 1, belongs to the ROR subfamily of Tyr protein kinase family,a protein kinase superfamily. It has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo. Human ROR1 is a type I transmembrane protein with 937 amino acids (aa) in length. It contains a 29 aa signal sequence, a 377 aa extracellular domain (ECD), a 21 aa transmembrane segment, and a 510 aa cytoplasmic region. Human ROR1 shares 97% and 58% aa sequence identity with mouse ROR1 and human ROR2, respectively. ROR1 may act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling. ROR1 expressed strongly in human heart, lung and kidney, but weakly in the CNS. Its Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm.
仕様
- サイズ：50ug
- 種由来：Mouse
- 発現宿主：Human Cells
- 純度：> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：Q99JW5
- タグ種類：C-Fc
- アミノ酸配列：Gln24-Thr266
- 遺伝子構造：Recombinant Mouse EpCAM is produced by our Mammalian expression system and the target gene encoding Gln24-Thr266 is expressed with a Fc tag at the C-terminus.
- 活性：Immobilized Human CTSL2-His(Cat: PKSH032183) at 10μg/ml(100 μl/well) can bind Mouse EpCAM-Fc.
- 別名（遺伝子名）：Neurotrophic tyrosine kinase receptor-related 1; receptor tyrosine kinase-like orphan receptor 1; ROR1;tyrosine-protein kinase transmembrane receptor ROR1; Epithelial cell adhesion molecule; Tumor-associated calcium signal transducer 1;TROP1;CD326;EGP;EGP-2;Egp314;Ep-CAM;EpCAM1;GA733-2;gp40;Ly74;Tacsd1;Tacstd1
- 分子量：54.8 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229721-Elabscience-PKSM041339.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7826-51
Recombinant Mouse EpCAM/TROP-1 Protein (Fc Tag)(Active) 10ug
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89-7826-52
Recombinant Mouse EpCAM/TROP-1 Protein (Fc Tag)(Active) 50ug
|
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