89-7826-28 Recombinant Mouse IL1R1/CD121a Protein (His Tag) 50ug PKSM041327
[Elabscience]
特徴
- 背景：Mouse Interleukin 1 receptor, type I (IL-1R1) also known as CD121a (Cluster of Differentiation 121a), is an interleukin receptor. IL-1R1/CD121a is a cytokine receptor that belongs to the interleukin 1 receptor family.This protein is a receptor for interleukin 1 alpha (IL1A), interleukin 1 beta (IL1B), and interleukin 1 receptor antagonist (IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. An IL1 receptor accessory protein that can heterodimerize with the Type I receptor in the presence of IL1α or IL1βbut not IL1ra, was identified. This Type I receptor complex appears to mediate all the known IL1 biological responses. The receptor Type II has a short cytoplasmic domain and does not transduce IL1 signals. In addition to the membranebound form of IL1 RII, a naturallyoccurring soluble form of IL1 RII has been described. It has been suggested that the Type II receptor, either as the membranebound or as the soluble form, serves as a decoy for IL1 and inhibits IL1 action by blocking the binding of IL1 to the signaling Type I receptor complex.
仕様
- サイズ：50ug
- 種由来：Mouse
- 発現宿主：Human Cells
- 純度：> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：P13504
- タグ種類：C-His
- アミノ酸配列：Leu20-Lys338
- 遺伝子構造：Recombinant Mouse IL1R1 is produced by our Mammalian expression system and the target gene encoding Leu20-Lys338 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：Interleukin-1 receptor type 1;IL-1RT1; IL-1 RI;CD121b;IL-1R1;IL-iR;Il1r-1
- 分子量：38.1 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229709-Elabscience-PKSM041327.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7826-28
Recombinant Mouse IL1R1/CD121a Protein (His Tag) 50ug
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89-7826-27
Recombinant Mouse IL1R1/CD121a Protein (His Tag) 10ug
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