89-7825-69 Recombinant Mouse OX40/TNFRSF6 Protein (Fc Tag)(Active) 50ug PKSM041298
[Elabscience]
特徴
- 背景：OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed on CD4+ and CD8+ T cells upon engagement of the TCR by antigen presenting cells along with co-stimulation by CD40-CD40 Ligand and CD28-B7. The interaction between OX40 and OX40 ligand (OX40L) will occur when activated T cells bind to professional antigen-presenting cells (APCs). The T-cell functions, including cytokine production, expansion, and survival, are then enhanced by the OX40 costimulatory signals. OX40 signals are critical for controlling the function and differentiation of Foxp3+ regulatory T cells. OX40-OX40L interaction regulates T-cell tolerance, peripheral T-cell homeostasis, and T-cell-mediated inflammatory diseases.
仕様
- サイズ：50ug
- 種由来：Mouse
- 発現宿主：Human Cells
- 純度：> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：P47741
- タグ種類：C-Fc
- アミノ酸配列：Val20-Pro211
- 遺伝子構造：Recombinant Mouse OX40 is produced by our Mammalian expression system and the target gene encoding Val20-Pro211 is expressed with a Fc tag at the C-terminus.
- 活性：Immobilized Mouse OX40L-His(Cat: PKSM041119) at 2μg/ml(100 μl/well) can bind Mouse OX40-Fc. The ED50 of Mouse OX40-Fc is 4.204 ug/ml .
- 別名（遺伝子名）：Tumor necrosis factor receptor superfamily member 4;Tnfrsf4;OX40;CD134;Txgp1
- 分子量：48.1 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229680-Elabscience-PKSM041298.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7825-69
Recombinant Mouse OX40/TNFRSF6 Protein (Fc Tag)(Active) 50ug
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89-7825-68
Recombinant Mouse OX40/TNFRSF6 Protein (Fc Tag)(Active) 10ug
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