89-7825-47 Recombinant Mouse PRLR/Prolactin Receptor Protein (Fc Tag) 50ug PKSM041287
[Elabscience]
特徴
- 背景：The prolactin receptor (PRLR) is a member of the class I cytokine/lactogen receptor family which mediates the diverse cellular actions of prolactin in several tissues. PRLRs are expressed in normal and neoplastic human breast tissue, and in most breast cancer cells. PRLR contains an extracellular region that binds prolactin, a transmembrane region, and a cytoplasmatic region required for the activation of the Jak2–Stat5 signal transduction pathway by Prl which is essential for transcriptional activation of all known prolactin regulated genes. PRLRs have also been observed in ovarian follicular cells of mice, pigs, sheep, deer, and humans, as well as in luteal tissue in cow and horse ovaries. Furthermore, PRLR knockout mice exhibit failure of embryonic implantation, reduced number of mature oocytes, and low fertilization rates. Knockout females also display a reduced number of primary follicles.
仕様
- サイズ：50ug
- 種由来：Mouse
- 発現宿主：Human Cells
- 純度：> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：Q08501
- タグ種類：C-Fc
- アミノ酸配列：Gln20-Asp229
- 遺伝子構造：Recombinant Mouse Prolactin receptor is produced by our Mammalian expression system and the target gene encoding Gln20-Asp229 is expressed with a Fc tag at the C-terminus.
- 別名（遺伝子名）：Prolactin receptor; PRL-R; Prlr; Prolactin R; PRLR
- 分子量：51.7 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229669-Elabscience-PKSM041287.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7825-46
Recombinant Mouse PRLR/Prolactin Receptor Protein (Fc Tag) 10ug
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89-7825-47
Recombinant Mouse PRLR/Prolactin Receptor Protein (Fc Tag) 50ug
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