特徴
- 背景:Serine protease inhibitor A3N(Serpin A3N) is a serine protease inhibitor that is structurally related to α1 antichymotrypsin encoded by the SERPINA3 gene. Serpin A3N is highly expressed in brain, testis, lung, thymus, and spleen. It is expressed with low levels in bone marrow, kidney and skeletal muscle. Serpin A3N secreted by Sertoli cells may regulate the activity of locally produced Granzyme B. Granzyme B inhibition by Serpin A3N may therefore regulate Granzyme Bmediated killing by cytotoxic lymphocytes, providing a means to disable cellmediated immune responses.
仕様
- サイズ:10ug
- 種由来:Mouse
- 発現宿主:Human Cells
- 純度:> 95% as determined by reducing SDS-PAGE.
- エンドトキシン濃度:< 1.0 EU per μg as determined by the LAL method.
- アクセッションNo.:Q91WP6
- タグ種類:C-His
- アミノ酸配列:Phe21-Lys418
- 遺伝子構造:Recombinant Mouse Serpin A3N is produced by our Mammalian expression system and the target gene encoding Phe21-Lys418 is expressed with a 6His tag at the C-terminus.
- 別名(遺伝子名):Serine protease inhibitor A3N; Serpin A3N; Serpina3n; Spi2
- 分子量:45.6 kDa
- 組成:Supplied as a 0.2 μm filtered solution of 20mM Tris,150mM NaCl,pH8.0 .
- 保存条件:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-229661-Elabscience-PKSM041279.pdf
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7825-30
Recombinant Mouse Serpin A3N Protein (His Tag) 10ug
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89-7825-31
Recombinant Mouse Serpin A3N Protein (His Tag) 50ug
|
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