89-7825-21 Recombinant Mouse Thrombomodulin/THBD Protein (His Tag) 50ug PKSM041274
[Elabscience]
特徴
- 背景：Thrombomodulin is also known as CD141 antigen and blood dendritic cell antigen 3 (BDCA3), which is encoded by the THBD gene. The deduced amino acid sequence of mouse THBD predicts a signal peptide (aa 1 to 16) and a mature chain (aa 17 to 577) that consists of the following domains: C-type lectin, EGF-like, transmembrane and cytoplasmic. Mouse THBD is corresponding to the extracellular portion of the type I membrane protein. Predominantly synthesized by vascular endothelial cells, THBD inhibits coagulation and fibrinolysis. It functions as a cell surface receptor and an essential cofactor for active thrombin, which in turn activates protein C and thrombinactivatable fibrinolysis inhibitor (TAFI), also known as carboxypeptidase B2 (CPB2). In addition, THBD gene polymorphisims are associated with human disease and THBD plays a role in thrombosis, stroke, arteriosclerosis, and cancer.
仕様
- サイズ：50ug
- 種由来：Mouse
- 発現宿主：Human Cells
- 純度：> 90% as determined by reducing SDS-PAGE.
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：P15306
- タグ種類：C-His
- アミノ酸配列：Leu17-Ser517
- 遺伝子構造：Recombinant Mouse Thrombomodulin is produced by our Mammalian expression system and the target gene encoding Leu17-Ser517 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：Thrombomodulin; TM; Fetomodulin; CD141; BDCA-3; Thbd
- 分子量：54.6 kDa
- 組成：Supplied as a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH8.0.
- 保存条件：Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-229656-Elabscience-PKSM041274.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7825-21
Recombinant Mouse Thrombomodulin/THBD Protein (His Tag) 50ug
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89-7825-20
Recombinant Mouse Thrombomodulin/THBD Protein (His Tag) 10ug
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