89-7824-69 Recombinant Mouse CD16-2/FCGR4 Protein (His Tag)(Active) 10ug PKSM041244
[Elabscience]
特徴
- 背景：Fcgr4, also known as CD16-2, is one of the receptors for Fc region of IgG which involve in immune responses. Fcgr4 mainly functions in cellular response to lipopolysaccharide, NK T cell proliferation, regulation of sensory perception of pain, wound healing etc. Three groups are included for Fc γ receptors (FcR), and they are Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). Among these, CD64 possess high affinity even for monomeric IgG, while CD32 and CD16 display a relative lower affinity for IgG. Genes encodes these receptors are diverse differing by species and cell types. The aggregation of FcR having immunoreceptor tyrosine-based activation motifs (ITAMs) activates sequentially src family tyrosine kinases and syk family tyrosine kinases that connect transduced signals to common activation pathways shared with other receptors. FcR with ITAMs elicit cell activation, endocytosis, and phagocytosis. Fcgr4 belongs to Fc γ RIII (CD16) group.
仕様
- サイズ：10ug
- 種由来：Mouse
- 発現宿主：Human Cells
- 純度：> 95 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：NP_653142.2
- タグ種類：C-6His
- アミノ酸配列：Gly21-Gln203
- 遺伝子構造：Recombinant Mouse Low Affinity Immunoglobulin Gamma Fc Region Receptor IV is produced by our Mammalian expression system and the target gene encoding Gly21-Gln203 is expressed with a 6His tag at the C-terminus.
- 活性：Immobilized Human IgG1-Fc(Cat: PKSH032558) at 2μg/ml(100 μl/well) can bind Mouse FcgR4-His.
- 別名（遺伝子名）：Low Affinity Immunoglobulin Gamma Fc Region Receptor IV;FcgR4;4833442P21Rik;CD16-2;FcgammaRIV;Fcgr3a;FcgRIV;Fcrl3
- 分子量：21.9 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-139546-Elabscience-PKSM041244.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7824-69
Recombinant Mouse CD16-2/FCGR4 Protein (His Tag)(Active) 10ug
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89-7824-70
Recombinant Mouse CD16-2/FCGR4 Protein (His Tag)(Active) 50ug
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