89-7823-59 ［取扱停止］Recombinant Mouse b-NGF/NGFB Protein (aa 122-241)(Active) 50ug PKSM041189
[Elabscience]
特徴
- 背景：NGF is the first member discovered in the Neurotrophin family, which includes brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4). These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Mouse beta -NGF is a homodimer of two 120 amino acid polypeptides. It shares approximately 90% homology at the amino acid level with human beta -NGF and 95.8% with rat beta -NGF. NGF signaling has been shown to play an important role in neuroprotection and repair. b-NGF acts as a growth and differentiation factor for B lymphocytes, and enhances B-cell survival. It is a potent neurotrophic factor that signals through its receptor b-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems.
仕様
- サイズ：50ug
- 種由来：Mouse
- 発現宿主：E.coli
- 純度：> 95 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：P01139
- アミノ酸配列： Ser122-Gly241
- 遺伝子構造：Recombinant Mouse beta-Nerve Growth Factor is produced by our E.coli expression system and the target gene encoding Ser122-Gly241 is expressed.
- 活性：Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells The ED50 for this effect is 0.3-1.5 ng/ml.
- 別名（遺伝子名）：Beta-nerve growth factor; Beta-NGF; Ngf
- 分子量：13.5 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM Tris,150mM NaCl,pH8.0.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-107455-Elabscience-PKSM041189.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7823-58
Recombinant Mouse b-NGF/NGFB Protein (aa 122-241)(Active) 10ug
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89-7823-59
Recombinant Mouse b-NGF/NGFB Protein (aa 122-241)(Active) 50ug
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