89-7823-33 Recombinant Mouse TNF-alpha/TNFA Protein (aa 89-235)(Active) 50ug PKSM041176
[Elabscience]特徴
- 背景:Tumor Necrosis Factor (TNF) is a member of the Tumor Necrosis Factor family. TNF exists as a homotrimer and interacts with SPPL2B. TNF is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. TNF is a key cytokine in the development of several inflammatory disorders. It contributes to the development of type 2 diabetes throught its effects on insulin resistance and fatty acid metabolism.
仕様
- サイズ:50ug
- 種由来:Mouse
- 発現宿主:E.coli
- 純度:> 95 % as determined by SDS-PAGE
- エンドトキシン濃度:< 1.0 EU per μg as determined by the LAL method.
- アクセッションNo.:P06804
- アミノ酸配列: Asp89-Leu235
- 遺伝子構造:Recombinant Mouse Tumor Necrosis Factor alpha is produced by our E.coli expression system and the target gene encoding Asp89-Leu235 is expressed.
- 活性:Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is 2-8 pg/ml.
- 別名(遺伝子名):Tumor Necrosis Factor; Cachectin; TNF-Alpha; Tumor Necrosis Factor Ligand Superfamily Member 2; TNF-a; Tumor Necrosis Factor; Membrane Form; Tumor Necrosis Factor; Tnf;Tnfsf2;DIF;TNF-alpha;Tnfa;TNFalpha;Tnfsf1a;TNFSF2
- 分子量:16.4 kDa
- 組成:Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-107442-Elabscience-PKSM041176.pdf
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
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89-7823-32
Recombinant Mouse TNF-alpha/TNFA Protein (aa 89-235)(Active) 10ug
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89-7823-33
Recombinant Mouse TNF-alpha/TNFA Protein (aa 89-235)(Active) 50ug
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