89-7823-13 ［取扱停止］Recombinant Mouse RANKL/TNFSF11 Protein (Active) 50ug PKSM041166
[Elabscience]
特徴
- 背景：Mouse tumor necrosis factor ligand superfamily member 11(Tnfsf11) is a member of the tumor necrosis factor (TNF) cytokine family. Tnfsf11 is widely expressed in cells including T cells and T cell rich organs, such as thymus and lymph nodes. This cytokine can bind to TNFRSF11B/OPG andTNFRSF11A/RANK. Tnfsf11 is involved in a number of fundamental biological processes such as acting as regulator of interactions between T-cells and dendritic cells, the regulation of the T-cell-dependent immune response and enhancing bone-resorption in humoral hypercalcemia of malignancy. It augments the ability of dendritic cells to stimulate naive T-cell proliferation.
仕様
- サイズ：50ug
- 種由来：Mouse
- 発現宿主：E.coli
- 純度：> 95 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：O35235
- アミノ酸配列： Gln137-Asp316
- 遺伝子構造：Recombinant Mouse TNF ligand superfamily member 11 is produced by our E.coli expression system and the target gene encoding Gln137-Asp316 is expressed.
- 活性：Measured by its ability to induce osteoclast differentiation of RAW 264.7 mouse monocyte/macrophage cells. The ED50 for this effect is 0.2-1 ng/ml.
- 別名（遺伝子名）：Tumor necrosis factor ligand superfamily member 11;Tnfsf11;Osteoclast differentiation factor;ODF;Osteoprotegerin ligand;OPGL;Receptor activator of nuclear factor kappa-B ligand;RANKL;TNF-related activation-induced cytokine;TRANCE;CD254
- 分子量：20.1 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mMTris,150mMNaCl,1mMEDTA,pH8.0.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-107432-Elabscience-PKSM041166.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7823-12
Recombinant Mouse RANKL/TNFSF11 Protein (Active) 10ug
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89-7823-13
Recombinant Mouse RANKL/TNFSF11 Protein (Active) 50ug
|
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