89-7822-62 Recombinant Mouse SerpinD1/HCF2 Protein (His Tag) 50ug PKSM041140
[Elabscience]特徴
- 背景:SerpinD1, also known as heparin cofactor II(HC-II), is a member of Serpin superfamily of the serine proteinase inhibitors. It is a single chain glycoprotein with a size of 66.5 kDa and is secreted from hepatocytes. HC-II acts as a thrombin inhibitor in the coagulation cascade, in a glycosaminoglycan-dependent pathway using the release of a sequestered hirudin-like N-terminal tail for interaction with thrombin. This serpin belongs to multiple member group V2 of vertebrate serpin classification. It has been suggested that HC-II is a predictor of decreased atherosclerosis in the elderly and protective against atherosclerosis in mice. HCII can used as a predictive biomarker and therapeutic target for atherosclerosis.
仕様
- サイズ:50ug
- 種由来:Mouse
- 発現宿主:Human Cells
- 純度:> 95 % as determined by SDS-PAGE
- エンドトキシン濃度:< 1.0 EU per μg as determined by the LAL method.
- アクセッションNo.:P49182
- タグ種類:C-6His
- アミノ酸配列:Glu24-Ser478
- 遺伝子構造:Recombinant Mouse Serine Protease Inhibitor-clade D1 is produced by our Mammalian expression system and the target gene encoding Glu24-Ser478 is expressed with a 6His tag at the C-terminus.
- 別名(遺伝子名):Heparin cofactor 2; Heparin cofactor II; HC-II; Protease inhibitor leuserpin-2; Serpin D1
- 分子量:53.1 kDa
- 組成:Lyophilized from a 0.2 μm filtered solution of 20mM HEPES,150mM NaCl,pH7.4.
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-107406-Elabscience-PKSM041140.pdf
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89-7822-61
Recombinant Mouse SerpinD1/HCF2 Protein (His Tag) 10ug
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89-7822-62
Recombinant Mouse SerpinD1/HCF2 Protein (His Tag) 50ug
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