89-7821-13 Recombinant Mouse IGFBP-5/IGFBP5 Protein (His Tag) 50ug PKSM041058
[Elabscience]
特徴
- 背景：Mouse Insulin-like growth factor-binding protein 5(IGFBP-5) belongs to the superfamily of insulin-like growth factor (IGF) binding proteins. It contains 1 IGFBP N-terminal domain and 1 thyroglobulin type-1 domain. Mouse IGFBP-5 shows 97% aa sequence identity with those of human and rat IGFBP-5. It is expressed mostly in kidney, uterus and gastrocnemius muscle. It also expressed by fibroblasts, myoblasts and osteoblasts, making it the predominant IGFBP found in bone extracts. IGFBP-5 has a strong affinity for hydroxyapatite, allowing it to bind to bone cells. When bound to extracelluar matrix, IGFBP-5 is protected from proteolysis and potentiates IGF activity, but when it is soluble, IGFBP-5 is cleaved to a biologically inactive 21 kDa fragment. IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
仕様
- サイズ：50ug
- 種由来：Mouse
- 発現宿主：Human Cells
- 純度：> 90 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：Q07079
- タグ種類：C-6His
- アミノ酸配列：Leu20-Glu271
- 遺伝子構造：Recombinant Mouse Insulin-like growth factor-binding protein 5 is produced by our Mammalian expression system and the target gene encoding Leu20-Glu271 is expressed with a 6His tag at the C-terminus.
- 別名（遺伝子名）：BP-5; IGFBP-5; IGF-binding protein 5; Insulin-like growth factor-binding protein 5;
- 分子量：29.3 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-107331-Elabscience-PKSM041058.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7821-13
Recombinant Mouse IGFBP-5/IGFBP5 Protein (His Tag) 50ug
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89-7821-12
Recombinant Mouse IGFBP-5/IGFBP5 Protein (His Tag) 10ug
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