特徴
- 背景：Chemokine (C-X-C motif) ligand 9 (CXCL9, MIG), is a small cytokine belonging to the CXC chemokine family. CXCL9 functions as one of the three ligands of chemokine receptor CXCR3 which is a G protein-coupled receptor found predominantly on T cells. It together with CXCL10 and CXCL11, may activate CXCR3 by binding to it. CXCL9 serves as a cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. It has been observed that tumour endothelial cells secrete high levels of CXCL9 in all, and CXCL10 in most melanoma metastases. it plays an important role in CD4+ T lymphocyte recruitment and development of CAV, MOMA-2+ macrophages are the predominant recipient-derived source of CXCL9, and recipient CD4 lymphocytes are necessary for sustained CXCL9 production and CAV development in this model.
仕様
- サイズ：10ug
- 種由来：Mouse
- 発現宿主：E.coli
- 純度：> 95 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：P18340
- アミノ酸配列：Thr22-Thr126?
- 遺伝子構造：Recombinant Mouse C-X-C Motif Chemokine 9 is produced by our E.coli expression system and the target gene encoding Thr22-Thr126? is expressed.
- 別名（遺伝子名）：C-X-C motif chemokine 9;Cxcl9;Gamma-interferon-induced monokine;Monokine induced by interferon-gamma;MIG;Small-inducible cytokine B9;Scyb9
- 分子量：12.3 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-107274-Elabscience-PKSM040997.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7820-02
Recombinant Mouse CXCL9 Protein 50ug
|
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89-7820-01
Recombinant Mouse CXCL9 Protein 10ug
|
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