特徴
- 背景:C-C motif chemokine 9(CCL9) is an 11 kDa, secreted, monomeric polypeptide that belongs to the beta (or CC) intercrine family of chemokines. It is expressed mainly in the liver, lung, and the thymus, although some expression has been detected in a wide variety of tissues except brain. Monokine has inflammatory, pyrogenic and chemokinetic properties. It circulates at high concentrations in the blood of healthy animals. Binding to a high-affinity receptor,it activates calcium release in neutrophils. It also inhibits colony formation of bone marrow myeloid immature progenitors. CCL9 can activate osteoclasts through its receptor CCR1 (the most abundant chemokine receptor found on osteoclasts) suggesting an important role for CCL9 in bone resorption.
仕様
- サイズ:50ug
- 種由来:Mouse
- 発現宿主:E.coli
- 純度:> 90 % as determined by SDS-PAGE
- エンドトキシン濃度:< 1.0 EU per μg as determined by the LAL method.
- アクセッションNo.:P51670
- アミノ酸配列: Gln22-Gln122
- 遺伝子構造:Recombinant Mouse C-C Motif Chemokine 9 is produced by our E.coli expression system and the target gene encoding Gln22-Gln122 is expressed.
- 別名(遺伝子名):C-C motif chemokine 9; CCF18; Macrophage inflammatory protein 1-gamma; Macrophage inflammatory protein-related protein 2; Small-inducible cytokine A9; Scya10;Scya9 and CCL9.
- 分子量:11.6 kDa
- 組成:Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl,300mM NaCl,pH8.0.
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-107261-Elabscience-PKSM040984.pdf
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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89-7819-75
Recombinant Mouse CCL9/MIP-1-gamma Protein 50ug
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89-7819-74
Recombinant Mouse CCL9/MIP-1-gamma Protein 10ug
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