89-7819-41 Recombinant Mouse B7-H4/VTCN1 Protein (aa 25-256, Fc Tag) 50ug PKSM040966
[Elabscience]
特徴
- 背景：Mouse V-set domain-containing T-cell activation inhibitor 1/VTCN1/B7-H4 is glycosylated member of the B7 family of immune co-stimulatory proteins. B7-H4 consists of extracellular domain (ECD) with one Ig-like V-set domain and one Ig-like C2-set domain. It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. It also involved in promoting epithelial cell transformation.
仕様
- サイズ：50ug
- 種由来：Mouse
- 発現宿主：Human Cells
- 純度：> 95 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg as determined by the LAL method.
- アクセッションＮｏ．：Q7TSP5
- タグ種類：C-Fc
- アミノ酸配列：Leu25-Ser256
- 遺伝子構造：Recombinant Mouse B7 Homolog 4 is produced by our Mammalian expression system and the target gene encoding Leu25-Ser256 is expressed with a Fc tag at the C-terminus.
- 別名（遺伝子名）：V-set domain containing T-cell activation inhibitor 1;B7 homolog 4;Protein B7S1;B7-H4;VTCN1;B7h4;B7s1;B7x;BC032925
- 分子量：52.7 kDa
- 組成：Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-107244-Elabscience-PKSM040966.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
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89-7819-40
Recombinant Mouse B7-H4/VTCN1 Protein (aa 25-256, Fc Tag) 10ug
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89-7819-41
Recombinant Mouse B7-H4/VTCN1 Protein (aa 25-256, Fc Tag) 50ug
|
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