89-7818-13 ［取扱停止］Recombinant Mouse CD32/FCGR2B Protein (His&AVI Tag)(Active) 50ug PKSM040901
[Elabscience]
特徴
- 背景：Receptors for Fc portion of IgG (Fcγ Rs) are members of the Ig superfamily, and are divided into three classes designated Fcγ RI (CD64), Fcγ RII (CD32), and Fcγ RIII (CD16). CD32 protein is a low affinity receptor for IgG that binds only IgG immune complexes and is expressed on a diverse range of cells such as monocytes, macrophages, neutrophils, eosinophils, platelets, and B cells. Human CD32 class is encoded by three closely related genes, and designated Fcγ RII A, B, and C which share 94-99% amino acid identity in their extracellular domains but differ substantially in their transmembrane and cytoplasmic domains. CD32 is involved in a number of immune responses including antibody-dependent cell-mediated cytotoxicity, clearance of immune complexes, release of inflammatory mediators, and regulation of antibody production.
仕様
- サイズ：50ug
- 種由来：Mouse
- 発現宿主：HEK293 Cells
- 純度：> 98 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションＮｏ．：NP_001070657.1
- タグ種類：C-His-AVI
- アミノ酸配列：Met 1-Arg 217
- 遺伝子構造：A DNA sequence encoding the extracellular domain (Met 1-Arg 217) of mouse FGGR2B (NP_001070657.1) as fused with a c-terminal polyhistidine tagged AVI tag at the C-terminus.
- 活性：Immobilized mouse CD32-AVI-His at 10 μg/ml (100 μl/well) can bind biotinylated Human IgG1, The EC50 of biotinylated Human IgG1 is 0.08-0.18 μg/ml.
- 別名（遺伝子名）：AI528646;CD32;F630109E10Rik;Fcgr2;Fcgr2a;FcgRII;Fcr-2;Fcr-3;fcRII;Fc[g]RII;Ly-17;Ly-m20;LyM-1
- 分子量：23.9 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-107207-Elabscience-PKSM040901.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7818-14
Recombinant Mouse CD32/FCGR2B Protein (His&AVI Tag)(Active) 100ug
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89-7818-13
Recombinant Mouse CD32/FCGR2B Protein (His&AVI Tag)(Active) 50ug
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