89-7817-35 Recombinant Mouse APCS/SAP Protein (His Tag)(Active) 100ug PKSM040858
[Elabscience]
特徴
- 背景：Serum amyloid P component (SAP) is the identical serum form of amyloid P component (AP), a highly preserved plasma protein named for its ubiquitous presence in amyloid deposits. As a normal plasma protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". Serum amyloid P component represents another member of the pentraxin family, a highly conserved group of molecules that may play a role in innate immunity. SAP is a key negative regulator for innate immune responses to DNA and may be partly responsible for the insufficient immune responses after DNA vaccinations in humans. SAP suppression may be a novel strategy for improving efficacy of human DNA vaccines and requires further clinical investigations.
仕様
- サイズ：100ug
- 種由来：Mouse
- 発現宿主：HEK293 Cells
- 純度：> 90 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションＮｏ．：NP_035448.2
- タグ種類：C-His
- アミノ酸配列：Met 1-Glu 224
- 遺伝子構造：A DNA sequence encoding the mouse APCS (NP_035448.2) (Met 1-Glu 224) precursor was expressed with a C-terminal polyhistidine tag.
- 活性：1. Measured by its binding ability in a functional ELISA. Immobilized mouse APCS at 10 μg/ml (100 μl/well) can bind biotinylated human Fibronectin Fragment 2 with a linear ranger of 0.625-5 μg/ml.2. Measured by its ability to bind mouse CD64-AVI in a functional ELISA.
- 別名（遺伝子名）：APCS; PTX2; SAP; 9.5S alpha-1-glycoprotein; Serum amyloid P; MGC88159; PTX2serum amyloid P-component; SAP pentaxin-related
- 分子量：25.3 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-38881-Elabscience-PKSM040858.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7817-34
Recombinant Mouse APCS/SAP Protein (His Tag)(Active) 50ug
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89-7817-35
Recombinant Mouse APCS/SAP Protein (His Tag)(Active) 100ug
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