89-7817-01 ［取扱停止］Recombinant Mouse TNFRSF19/TROY Protein (His Tag) 200ug PKSM040839
[Elabscience]
特徴
- 背景：Tumor necrosis factor receptor superfamily, member 19 (TNFRSF19), also known as TAJ-alpha or TROY, is a member of the TNF-receptor superfamily. TNFRSF19/TROY expression is detected in the pulmonary epithelium and the ductal epithelium of the prostate and parotid glands. TNFRSF19/TROY expression is detected in some adenocarcinoma cell lines that arise from this tissue. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. TNFRSF19/TROY is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. TNFRSF19/TROY was negatively regulated by adipogenic transcription factor CCAAT/enhancer-binding proteins (C/EBP). TNFRSF19 signals activation of the Jnk pathway and induces cell death. Overexpression of TNFRSF19 also signals NFB activation, comparable and similar to that by p75NGFR. TNFRSF19/TROY is capable of activating key signaling pathways of the TNF receptor family, and its predominant expression patterns suggest that it plays a role in the growth and regulation of epithelial tissues.
仕様
- サイズ：200ug
- 種由来：Mouse
- 発現宿主：HEK293 Cells
- 純度：> 95 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションＮｏ．：NP_001157627.1
- タグ種類：C-His
- アミノ酸配列：Met 1-Leu 170
- 遺伝子構造：A DNA sequence encoding the extracellular domain (Met 1-Leu 170) of mouse TNFRSF19 (NP_001157627.1) was fused with a polyhistidine tag at the C-terminus.
- 別名（遺伝子名）：AL023044;AW123854;TAJ;TAJ-ALPHA;TRADE;Troy
- 分子量：17 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-107187-Elabscience-PKSM040839.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7816-99
Recombinant Mouse TNFRSF19/TROY Protein (His Tag) 100ug
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89-7817-01
Recombinant Mouse TNFRSF19/TROY Protein (His Tag) 200ug
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