89-7814-53 ［取扱停止］Recombinant Mouse Carboxypeptidase B1/CPB1 Protein (His Tag)(Active) 10ug PKSM040708
[Elabscience]
特徴
- 背景：Carboxypeptidase B1, also well known as pancreatic procarboxypeptidase B (PCPB), is a highly pancreas -specific protein (PASP), and has been identified previously as a serum marker for acute pancreatitis and pancreatic graft rejection. As the prototype for those human exopeptidases that cleave off basic C-terminal residues, CPB1 specifically cleaves the C-terminal Arg and Lys residues with a preference for Arg. The B1 and B2 forms of procarboxypeptidase B differ from each other mainly in isoelectric point.The deduced amino acid sequence of PCPB predicts a 416-amino acid preproenzyme consisting of a 15-aa signal peptide, a 95-aa activation peptide and a 307-aa mature chain. The secreted PCPB zymogen is converted to enzymatically active CPB1 by limited proteolysis by trypsin.
仕様
- サイズ：10ug
- 種由来：Mouse
- 発現宿主：HEK293 Cells
- 純度：> 94 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションＮｏ．：NP_083982.1
- タグ種類：C-His
- アミノ酸配列：Met 1-Tyr 415
- 遺伝子構造：A DNA sequence encoding the mouse CPB1 (NP_083982.1) precursor (Met 1-Tyr 415) was expressed, with a C-terminal polyhistidine tag.
- 活性：Measured by its ability to cleave a colorimetric peptide substrate, Hippuryl-Arg. The specific activity is >5,000 pmoles/min/μg.
- 別名（遺伝子名）：0910001A18Rik;1810063F02Rik;2210008M23Rik;AI504870
- 分子量：47.5 kDa
- 組成：Lyophilized from sterile 20mM MES, 150mM NaCl, pH 6.5
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-38782-Elabscience-PKSM040708.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7814-54
Recombinant Mouse Carboxypeptidase B1/CPB1 Protein (His Tag)(Active) 20ug
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89-7814-53
Recombinant Mouse Carboxypeptidase B1/CPB1 Protein (His Tag)(Active) 10ug
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