89-7814-39 ［取扱停止］Recombinant Mouse THSD1/TMTSP Protein (His Tag) 50ug PKSM040701
[Elabscience]
特徴
- 背景：Thrombospondin type-1 domain-containing protein 1, also known as transmembrane molecule with thrombospondin module, THSD1 and TMTSP, is a single-pass type I membrane protein which contains one TSP type-1 domain. THSD1 is a multi-domain, multi-functional glycoprotein synthesized by many cells. Matricellular THSD1 modulates cell adhesion and proliferation. It is involved in angiogenesis, inflammation, wound healing and cancer. In vitro, nanomolar concentrations of Thrombospondin-1 are required to alter endothelial and vascular smooth muscle cell adhesion, proliferation, motility, and survival. As a major platelet protein, for a long time it was postulated to control hemostasis via platelet aggregate stabilization. THSD1 is a potent angiogenesis inhibitor, and down-regulation of THSD1 has been suggested to alter tumor growth by modulating angiogenesis in a variety of tumor types.
仕様
- サイズ：50ug
- 種由来：Mouse
- 発現宿主：HEK293 Cells
- 純度：> 95 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションＮｏ．：NP_062522.1
- タグ種類：C-His
- アミノ酸配列：Met 1-Asn 412
- 遺伝子構造：A DNA sequence encoding the extracellular domain of mouse THSD1 (NP_062522.1) (Met 1-Asn 412) was expressed, with a C-terminal polyhistidine tag.
- 別名（遺伝子名）：4833423O18Rik;Tmtsp
- 分子量：45 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-38778-Elabscience-PKSM040701.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7814-40
Recombinant Mouse THSD1/TMTSP Protein (His Tag) 100ug
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89-7814-39
Recombinant Mouse THSD1/TMTSP Protein (His Tag) 50ug
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