89-7812-97 ［取扱停止］Recombinant Mouse Factor D Protein (aa 1-258, His Tag) 20ug PKSM040626
[Elabscience]
特徴
- 背景：Complement factor D, also known as Adipsin, C3 convertase activator, Properdin factor D and CFD is a secreted protein which belongs to the peptidase S1 family. CFD / Adipsin contains one peptidase S1 domain. Complement factor D ( CFD / Adipsin ) is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. Complement factor D ( CFD / Adipsin ) has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Complement factor D ( CFD / Adipsin ) cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. Complement factor D ( CFD / Adipsin ) is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Defects in CFD / Adipsin are the cause of complement factor D deficiency (CFD deficiency) which predisposes to invasive meningococcal disease.
仕様
- サイズ：20ug
- 種由来：Mouse
- 発現宿主：HEK293 Cells
- 純度：> 98 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションＮｏ．：P03953-2
- タグ種類：C-His
- アミノ酸配列：Met 1-Ser 258
- 遺伝子構造：A DNA sequence encoding the full length of mouse CFD isoform 2 (P03953-2) (Met 1-Ser 258) was expressed, with a polyhistidine tag at the C-terminus.
- 別名（遺伝子名）：Complement factor D; 28 kDa adipocyte protein; Adipsin; C3 convertase activator; Properdin factor D; Cfd; Adn; Df
- 分子量：27.4 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-107126-Elabscience-PKSM040626.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7812-98
Recombinant Mouse Factor D Protein (aa 1-258, His Tag) 50ug
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89-7812-97
Recombinant Mouse Factor D Protein (aa 1-258, His Tag) 20ug
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