89-7812-91 ［取扱停止］Recombinant Mouse TGFBR3/Betaglycan Protein (His Tag) 50ug PKSM040623
[Elabscience]
特徴
- 背景：Betaglycan also known as transforming growth factor beta receptor III (TGFBR3), is a cell-surface chondroitin sulfate / heparan sulfate proteoglycan. TGFBR3 is a transforming growth factor (TGF)-beta type III receptor. This receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. TGFBR3 is the TGF-β component most commonly downregulated among localized human prostate cancer studies. TGFBR3 knockdown led to focus formation and enhanced expression of CD133, a marker found on prostate cancer stem cells. TGFBR3 is an accessory receptor that binds to and modulates the activities of both transforming growth factor-beta (TGFβ) and inhibin, two members of the TGFβ superfamily of growth factors that regulate many aspects of reproductive biology. TGFBR3 is known to be expressed in adult testis and ovary, but little is known about this receptor during gonadogenesis.
仕様
- サイズ：50ug
- 種由来：Mouse
- 発現宿主：HEK293 Cells
- 純度：> 95 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションＮｏ．：NP_072075.2
- タグ種類：C-His
- アミノ酸配列：Met 1-Arg 399
- 遺伝子構造：A DNA sequence encoding the extracellular domain of mouse TGFBR3 (NP_072075.2) (Met 1-Arg 399) was expressed, with a polyhistidine tag at the C-terminus.
- 別名（遺伝子名）：1110036H20Rik;AU015626;AW215636;TBRIII
- 分子量：86.3 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-38724-Elabscience-PKSM040623.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7812-92
Recombinant Mouse TGFBR3/Betaglycan Protein (His Tag) 100ug
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89-7812-91
Recombinant Mouse TGFBR3/Betaglycan Protein (His Tag) 50ug
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