89-7812-87 ［取扱停止］Recombinant Mouse SPARCL1/SPARC-like 1 Protein (His Tag) 20ug PKSM040621
[Elabscience]
特徴
- 背景：SPARC-like protein 1 (SPARCL1; also known as SC1, high endothelial venule protein, or hevin) is an extracellular matrix-associated, secreted glycoprotein belonging to the secreted protein acidic and rich in cysteine (SPARC) family of matricellular proteins. It contains three conserved structural domains that are implicated in the regulation of cell adhesion, migration, and proliferation. SPARCL1 is expressed during embryogenesis and tissue remodeling and is especially prominent in brain and vasculature. Its down-regulation in a number of cancers and the possibility of its functional compensation by SPARC has led to recent interest in hevin as a tumor suppressor and regulator of angiogenesis. SPARCL1 has antiadhesive properties, and loss of SPARCL1 expression is associated with increased proliferative activity and cell cycle progression. It is suggested that it may influence multiple cellular processes during distinct stages of brain development and function. In addition, SPARCL1 can influence the function of astroglial cells in the developing and mature central nervous system (CNS).
仕様
- サイズ：20ug
- 種由来：Mouse
- 発現宿主：HEK293 Cells
- 純度：> 90 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションＮｏ．：NP_034227.3
- タグ種類：N-His
- アミノ酸配列：Tyr368-Phe650
- 遺伝子構造：A DNA sequence encoding the mouse Sparcl1 (NP_034227.3) (Tyr368-Phe650) was expressed with a polyhistidine tag at the N-terminus.
- 別名（遺伝子名）：Ecm2;hevin;mast9;Sc1
- 分子量：34.8 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-107123-Elabscience-PKSM040621.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7812-88
Recombinant Mouse SPARCL1/SPARC-like 1 Protein (His Tag) 100ug
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89-7812-87
Recombinant Mouse SPARCL1/SPARC-like 1 Protein (His Tag) 20ug
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