89-7812-82 Recombinant Mouse Peroxiredoxin 1/PRDX1 Protein (His Tag) 50ug PKSM040618
[Elabscience]
特徴
- 背景：Peroxiredoxin-1, also known as Thioredoxin peroxidase 2, Natural killer cell-enhancing factor A, PRDX1, and PAGA, is a member of the ahpC/TSA family. Peroxiredoxin-1 is constitutively expressed in most human cells. It is induced to higher levels upon serum stimulation in untransformed and transformed cells. Peroxiredoxins (PRDXs) are a family of antioxidant enzymes that are also known as scavengers of peroxide in mammalian cells. The overexpression of Peroxiredoxin-1, which is one of the peroxiredoxins that is a ubiquitously expressed protein, was related to a poor prognosis in several types of human cancers. Peroxiredoxin-1 is involved in redox regulation of the cell. It reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin and may play an important role in eliminating peroxides generated during metabolism. Peroxiredoxin-1 Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2. The reduced Peroxiredoxin-1 expression is an important factor in esophageal squamous cancer progression and could serve as a useful prognostic marker.
仕様
- サイズ：50ug
- 種由来：Mouse
- 発現宿主：E.coli
- 純度：> 85 % as determined by SDS-PAGE
- エンドトキシン濃度：Please contact us for more information.
- アクセッションＮｏ．：P35700
- タグ種類：C-His
- アミノ酸配列：Met 1-Lys 199
- 遺伝子構造：A DNA sequence encoding the mouse PRDX1 (P35700) (Met 1-Lys 199) was expressed, with a C-terminal polyhistidine tag.
- 別名（遺伝子名）：MSP23;NkefA;OSF-3;OSF3;PAG;Paga;PrdxI;prx1;PrxI;Tdpx2;TDX2;TPxA
- 分子量：23.5 kDa
- 組成：Lyophilized from sterile PBS, 10% glycerol, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-38720-Elabscience-PKSM040618.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7812-82
Recombinant Mouse Peroxiredoxin 1/PRDX1 Protein (His Tag) 50ug
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89-7812-81
Recombinant Mouse Peroxiredoxin 1/PRDX1 Protein (His Tag) 20ug
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