89-7812-45 ［取扱停止］Recombinant Mouse EphB4/HTK Protein (Fc Tag)(Active) 100ug PKSM040599
[Elabscience]
特徴
- 背景：Ephrin type-B receptor 4 is a protein that in humans is encoded by the EPHB4 gene. It is a single-pass type I membrane protein belonging to the ephrin receptor subfamily of protein kinase superfamily. Members of the ephrin and Eph family are local mediators of cell function through largely contact-dependent processes in development and in maturity. Furthermore, EphB4 protein and the corresponding ligand Ephrin-B2 contribute to tumor growth in various human tumors. EphB4 protein has tumor suppressor activities and that regulation of cell proliferation, extracellular matrix remodeling, and invasive potential are important mechanisms of tumor suppression. Therefore, Ephrin-B2/EphB4 may be recognized as a novel prognostic indicator for cancers.
仕様
- サイズ：100ug
- 種由来：Mouse
- 発現宿主：HEK293 Cells
- 純度：> 97 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションＮｏ．：P54761-1
- タグ種類：C-Fc
- アミノ酸配列：Met 1-Ala 539
- 遺伝子構造：A DNA sequence encoding the mouse EPHB4 (P54761-1) extracellular domain (Met 1-Ala 539) was fused with the Fc region of human IgG1 at the C-terminus.
- 活性：1. Measured by its binding ability in a functional ELISA.2. Immobilized mouse EPHB2-His at 10 μg/mL (100 μl/well) can bind mouse EPHB4-Fc , The EC50 of mouse EPHB4-Fc is 15 ng/mL.
- 別名（遺伝子名）：AI042935;Htk;MDK2;Myk1;Tyro11
- 分子量：84.7 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-38706-Elabscience-PKSM040599.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7812-45
Recombinant Mouse EphB4/HTK Protein (Fc Tag)(Active) 100ug
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89-7812-46
Recombinant Mouse EphB4/HTK Protein (Fc Tag)(Active) 200ug
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