89-7812-06 Recombinant Mouse SLAMF8 Protein (His Tag)(Active) 100ug PKSM040579
[Elabscience]
特徴
- 背景：The signaling lymphocyte activation molecule (SLAM) family includes homophilic and heterophilic receptors that modulate both adaptive and innate immune responses. These receptors share a common ectodomain organization: a membrane-proximal immunoglobulin constant domain and a membrane-distal immunoglobulin variable domain that is responsible for ligand recognition. SLAM family of receptors is expressed by a wide range of immune cells. Through their cytoplasmic domain, SLAM family receptors associate with SLAM-associated protein (SAP)-related molecules, a group of cytoplasmic adaptors composed almost exclusively of an SRC homology 2 domain. SLAM family receptors, in association with SAP family adaptors, have crucial roles during normal immune reactions in innate and adaptive immune cells. Mouse SLAM family member 8, also known as B-lymphocyte activator macrophage expressed, BCM-like membrane protein, SLAMF8 and BLAME, is a single-pass type I membrane protein. It contains one Ig-like C2-type (immunoglobulin-like) domain. SLAMF8 / BLAME is expressed in lymph node, spleen, thymus and bone marrow. It may play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor.
仕様
- サイズ：100ug
- 種由来：Mouse
- 発現宿主：HEK293 Cells
- 純度：> 80 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションＮｏ．：NP_083360.2
- タグ種類：C-His
- アミノ酸配列：Met 1-Asp 231
- 遺伝子構造：A DNA sequence encoding the mouse SLAMF8 (NP_083360.2) extracellular domain (Met 1-Asp 231) was fused with the a polyhistidine tag at the C-terminus.
- 活性：Measured by its ability to bind biotinylated mouse SLAMF8 in a functional ELISA.
- 別名（遺伝子名）：SLAM family member 8; B-lymphocyte activator macrophage expressed; CD353; Slamf8; Blame;SBBI42
- 分子量：24.8 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-38689-Elabscience-PKSM040579.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7812-05
Recombinant Mouse SLAMF8 Protein (His Tag)(Active) 50ug
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89-7812-06
Recombinant Mouse SLAMF8 Protein (His Tag)(Active) 100ug
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