89-7811-99 Recombinant Mouse EphA6/EHK-2 Protein (Fc Tag)(Active) 200ug PKSM040576
[Elabscience]
特徴
- 背景：Ephrin type-A receptor 6, also known as EphA6 or EHK2, belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family which 16 known receptors (14 found in mammals) are involved: EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHA6, EPHA7, EPHA8, EPHA9, EPHA10, EPHB1, EPHB2, EPHB3, EPHB4, EPHB5, EPHB6. The Eph family of receptor tyrosine kinases (comprising EphA and EphB receptors) has been implicated in synapse formation and the regulation of synaptic function and plasticity6. Eph receptor−mediated signaling, which is triggered by ephrins7, probably modifies the properties of synapses during synaptic activation and remodeling. Ephrin receptors are components of cell signalling pathways involved in animal growth and development, forming the largest sub-family of receptor tyrosine kinases (RTKs). Ligand-mediated activation of Ephs induce various important downstream effects and Eph receptors have been studied for their potential roles in the development of cancer. In the vomeronasal system, Ephrin-A5/EphA6 interactions mediate attraction or adhesion rather than repulsion.
仕様
- サイズ：200ug
- 種由来：Mouse
- 発現宿主：HEK293 Cells
- 純度：> 90 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションＮｏ．：NP_031964.2
- タグ種類：C-Fc
- アミノ酸配列：Met 1-Gln 546
- 遺伝子構造：A DNA sequence encoding the extracellular domain of mouse EphA6 (NP_031964.2) (Met 1-Gln 546) was fused with the Fc region of human IgG1 at the C-terminus.
- 活性：Measured by its binding ability in a functional ELISA. Immobilized mouse EphrinA3 at 1 μg/ml (100 μl/well) can bind mouse EPHA6 / chimera with a linear ranger of 6.25-400 ng/ml.
- 別名（遺伝子名）：Ehk2;Hek12;m-ehk2
- 分子量：85 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-107115-Elabscience-PKSM040576.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7811-99
Recombinant Mouse EphA6/EHK-2 Protein (Fc Tag)(Active) 200ug
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89-7811-98
Recombinant Mouse EphA6/EHK-2 Protein (Fc Tag)(Active) 100ug
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