89-7811-83 Recombinant Mouse Semaphorin-4D/SEMA4D Protein (His Tag)(Active) 100ug PKSM040568
[Elabscience]
特徴
- 背景：Semaphorin 4D (SEMA4D or CD1) is a member of the semaphorin family of proteins and an important mediator of the movement and differentiation of multiple cell types, including those of the immune, vascular, and nervous systems. VEGF and SEMA4D had a positive correlation with the malignant degree of ovarian cancer, and SEMA4D can serve as an independent prognostic factor. SEMA4D was the first semaphorin described to have immune functions and serves important roles in T cell priming, antibody production, and cell-to-cell adhesion. Proteolytic cleavage of SEMA4D from the cell surface gives rise to a soluble fragment of SEMA4D (sSEMA4D). Similar to the transmembranal form, sSEMA4D is thought to have immunoregulatory properties.
仕様
- サイズ：100ug
- 種由来：Mouse
- 発現宿主：HEK293 Cells
- 純度：> 96 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションＮｏ．：NP_038688.2
- タグ種類：C-His
- アミノ酸配列：Met 1-Arg 733
- 遺伝子構造：A DNA sequence encoding the mouse SEMA4D (NP_038688.2) extracellular domain (Met 1-Arg 733) was expressed, with a C-terminal polyhistidine tag.
- 活性：Measured by its ability to bind human SEMA4A in a functional ELISA.
- 別名（遺伝子名）：SEMA4D;Semaphorin-4D;M-Sema G;Semaphorin-C-like 2;Semaphorin-J;Sema J;CD100;Semacl2;Semaj;coll-4;Semacl2;Semaj
- 分子量：80.2 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-38679-Elabscience-PKSM040568.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7811-83
Recombinant Mouse Semaphorin-4D/SEMA4D Protein (His Tag)(Active) 100ug
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89-7811-82
Recombinant Mouse Semaphorin-4D/SEMA4D Protein (His Tag)(Active) 50ug
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