89-7811-55 ［取扱停止］Recombinant Mouse BLMH/BLM Hydrolase Protein (His Tag)(Active) 20ug PKSM040554
[Elabscience]
特徴
- 背景：The papain superfamily member bleomycin hydrolase (BLMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution. The only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The papain superfamily member bleomycin hydrolase (BLMH) is a neutral cysteine protease with structural similarity to a 20S proteasome. Bleomycin (BLM), a clinically used glycopeptide anticancer agent. BLMH is an essential protectant against BLM-induced death and has an important role in neonatal survival and in maintaining epidermal integrity. Sequencing revealed several putative sites phosphorylated by different types of protein kinases, but no signal sequence, transmembrane domain, N-linked glycosylation site or DNA-binding motif.
仕様
- サイズ：20ug
- 種由来：Mouse
- 発現宿主：E.coli
- 純度：> 95 % as determined by SDS-PAGE
- エンドトキシン濃度：Please contact us for more information.
- アクセッションＮｏ．：NP_848760.1
- タグ種類：N-His
- アミノ酸配列：Asn 2-Glu 455
- 遺伝子構造：A DNA sequence encoding the mouse BLMH (NP_848760.1) (Asn 2-Glu 455) was expressed, with a polyhistide tag at the N-terminus.
- 活性：Measured by its ability to hydrolyze Met-AMC. The specific activity is >500 pmoles/min/μg.
- 別名（遺伝子名）：AI035728;Bh;Bmh
- 分子量：53.3 kDa
- 組成：Lyophilized from sterile 50mM Tris, 0.15M NaCl, 10% glycerol, pH 8.0
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-38669-Elabscience-PKSM040554.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7811-55
Recombinant Mouse BLMH/BLM Hydrolase Protein (His Tag)(Active) 20ug
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89-7811-54
Recombinant Mouse BLMH/BLM Hydrolase Protein (His Tag)(Active) 10ug
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