89-7811-46 ［取扱停止］Recombinant Mouse OMGP/OMG Protein (aa 1-245, His Tag) 20ug PKSM040549
[Elabscience]
特徴
- 背景：Oligodendrocyte-myelin glycoprotein, also known as OMG and OMGP, is a cell membrane protein which contains eight LRR (leucine-rich) repeats. OMG / OMGP is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes in the central nervous system (CNS). OMG / OMGP is a cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system. OMG / OMGP play roles in both the developing and adult central nervous system. OMG / OMGP participats in growth cone collapse and inhibition of neurite outgrowth through its interaction with NgR, the receptor for Nogo. This function requires its leucine-rich repeat domain, a highly conserved region in OMgp during mammal evolution. OMG / OMGP leucine-rich repeat domain is also implicated in the inhibition of cell proliferation. OMG / OMGP may also be involved in the formation and maintenance of myelin sheaths. Cell proliferation, neuronal sprouting and myelination are crucial processes involved in brain development and regeneration after injury.
仕様
- サイズ：20ug
- 種由来：Mouse
- 発現宿主：HEK293 Cells
- 純度：> 95 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションＮｏ．：Q63912
- タグ種類：C-His
- アミノ酸配列：Met 1-Thr 245
- 遺伝子構造：A DNA sequence encoding the amino acids (Met 1-Thr 245) of mouse OMGP (Q63912) was expressed, with a C-terminal polyhistidine tag.
- 別名（遺伝子名）：RP23-67E18.6, LNGFR, Tnfrsf16, p75, p75NGFR, p75NTR
- 分子量：27 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-38665-Elabscience-PKSM040549.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7811-46
Recombinant Mouse OMGP/OMG Protein (aa 1-245, His Tag) 20ug
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89-7811-47
Recombinant Mouse OMGP/OMG Protein (aa 1-245, His Tag) 50ug
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