89-7811-18 Recombinant Mouse IFNGR1/CD119 Protein (His Tag)(Active) 100ug PKSM040535
[Elabscience]
特徴
- 背景：The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD119 (cluster of differentiation 119), also known as IFNGR1 ( interferon gamma receptor 1), is part of the heterodimeric gamma interferon receptor which consists of IFNGR1 (CD119) and IFNGR2. The IFNGR1 gene encodes the ligand-binding chain (alpha) of the interteron receptor while IFNGR gene encodes the non-ligand binding partner. The ability of the interferon-γ was achieved through binding to the interferon receptor CD119. After binding, the products of activated T-lymphocytes interferon-γ exerts antiviral activity, growth inhibitory effect, and several immune- regulatory activities on a variety of cell types.
仕様
- サイズ：100ug
- 種由来：Mouse
- 発現宿主：HEK293 Cells
- 純度：> 98 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションＮｏ．：P15261
- タグ種類：C-His
- アミノ酸配列：Met 1-Asp 253
- 遺伝子構造：A DNA sequence encoding the mouse IFNGR1 (P15261) extracellular domain (Met 1-Asp 253) was expressed, with a polyhistidine tag at the C-terminus.
- 活性：Measured by its ability to bind with recombinant mouse IFNG-Fc in a functional ELISA.
- 別名（遺伝子名）：CD119;Ifgr;IFN-gammaR;Ifngr;Nktar
- 分子量：27.4 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-107103-Elabscience-PKSM040535.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7811-19
Recombinant Mouse IFNGR1/CD119 Protein (His Tag)(Active) 200ug
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89-7811-18
Recombinant Mouse IFNGR1/CD119 Protein (His Tag)(Active) 100ug
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