89-7811-01 Recombinant Mouse HER2/ErbB2 Protein (His Tag) 100ug PKSM040525
[Elabscience]
特徴
- 背景：Epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
仕様
- サイズ：100ug
- 種由来：Mouse
- 発現宿主：HEK293 Cells
- 純度：> 95 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションＮｏ．：P70424
- タグ種類：C-His
- アミノ酸配列：Met 1-Thr 653
- 遺伝子構造：A DNA sequence encoding the mouse ERBB2 (P70424) extracellular domain (Met 1-Thr 653) was expressed, with a C-terminal polyhistidine tag.
- 別名（遺伝子名）：c-erbB2;c-neu;Erbb-2;HER-2;HER2;l11Jus8;mKIAA3023;Neu
- 分子量：71.1 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-38650-Elabscience-PKSM040525.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7811-01
Recombinant Mouse HER2/ErbB2 Protein (His Tag) 100ug
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89-7810-99
Recombinant Mouse HER2/ErbB2 Protein (His Tag) 50ug
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