89-7810-91 [取扱停止]Recombinant Mouse CD59a/MAC-IP Protein (His Tag) 20ug PKSM040521
[Elabscience]特徴
- 背景:Protectin, a complement regulatory protein, also known as CD59, or MIRL (membrane inhibitor of reactive lysis) is a small protein that inhibits the complement membrane attack complex by binding C5b678 and preventing C9 from binding and polymerizing. The amino-terminal 25 amino acids represented a typical signal peptide sequence and the carboxy-terminal hydrophobic amino acids were characteristic for phosphatidylinositol-anchored proteins.It was found that the CD59/Protectin antigen is a small protein sometimes associated with larger components (45 and 80 kD) in urine. CD59/Protectin antigen was released from the surface of transfected COS cells by phosphatidylinositol-specific phospholipase C, demonstrating that it is attached to the cell membrane by means of a glycolipid anchor; it is therefore likely to be absent from the surface of affected erythrocytes in the disease paroxysmal nocturnal hemoglobinuria.
仕様
- サイズ:20ug
- 種由来:Mouse
- 発現宿主:HEK293 Cells
- 純度:> 92 % as determined by SDS-PAGE
- エンドトキシン濃度:< 1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションNo.:O55186
- タグ種類:C-His
- アミノ酸配列:Met 1-Lys 95
- 遺伝子構造:A DNA sequence encoding the mouse CD59a (O55186) (Met 1-Lys 95), without the pro peptide, was fused with a C-terminal polyhistidine tag.
- 別名(遺伝子名):AA987121;Cd59;protectin;RP24-297H17.1
- 分子量:9.7 kDa
- 組成:Lyophilized from sterile PBS, pH 7.4
- 保存条件:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク:https://www.elabscience.com/viewpdf-38647-Elabscience-PKSM040521.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7810-91
Recombinant Mouse CD59a/MAC-IP Protein (His Tag) 20ug
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89-7810-92
Recombinant Mouse CD59a/MAC-IP Protein (His Tag) 50ug
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