89-7810-85 ［取扱停止］Recombinant Mouse Syndecan-4/SDC4 Protein (aa 1-146, His Tag) 50ug PKSM040518
[Elabscience]
特徴
- 背景：SDC4 (Syndecan-4), also known as Syn4, is a transmembrane heparan sulfate proteoglycan that co-operates with integrins during cell-matrix interactions for the assembly of focal adhesions and actin stress fibers and in the phosphorylation of focal adhesion kinase (FAK) on Tyr397. Syndecan-4 plays roles in the formation of focal adhesions and stress fibers. The cytoplasmic domain of syndecan-4 interacts with a number of signalling and structural proteins, and both extracellular and cytoplasmic domains are necessary for regulated activation of associated transmembrane receptors. Syndecan-4/SDC4 is a heparan sulfate proteoglycan and works as a coreceptor for various growth factors. SDC4 deficiency limits neointimal formation after vascular injury by regulating vascular smooth muscle cells (VSMCs) proliferation and vascular progenitor cells (VPCs) mobilization. Therefore, SDC4 may be a novel therapeutic target for preventing arterial restenosis after angioplasty.
仕様
- サイズ：50ug
- 種由来：Mouse
- 発現宿主：HEK293 Cells
- 純度：> 95 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションＮｏ．：O35988
- タグ種類：C-His
- アミノ酸配列：Met 1-Val 146
- 遺伝子構造：A DNA sequence encoding the mouse SDC4 (O35988) extracellular domain (Met 1-Val 146) was expressed, fused with a C-terminal polyhistidine tag.
- 別名（遺伝子名）：AA959608;AW108331;ryudocan;Synd4;syndecan-4;SDC4;SYND4;Ryudocan core protein
- 分子量：14.9 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-38644-Elabscience-PKSM040518.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7810-86
Recombinant Mouse Syndecan-4/SDC4 Protein (aa 1-146, His Tag) 100ug
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89-7810-85
Recombinant Mouse Syndecan-4/SDC4 Protein (aa 1-146, His Tag) 50ug
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