89-7810-49 ［取扱停止］Recombinant Mouse LILRB3/LIR3/ILT5/CD85a Protein (His Tag) 50ug PKSM040497
[Elabscience]
特徴
- 背景：Leukocyte immunoglobulin-like receptor subfamily B member 3, also known as Leukocyte immunoglobulin-like receptor 3, Immunoglobulin-like transcript 5, Monocyte inhibitory receptor HL9, CD85 antigen-like family member A, CD85a and LILRB3, is a single-pass type I membrane protein which belongs to the leukocyte receptor cluster (LRC) present on 19q13.4. LILRB3 / CD85a contains four Ig-like C2-type (immunoglobulin-like) domains. LILRB3 / CD85a contains three copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases. LILRB3 / CD85a is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found.
仕様
- サイズ：50ug
- 種由来：Mouse
- 発現宿主：HEK293 Cells
- 純度：> 95 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションＮｏ．：AAC53219.1
- タグ種類：C-His
- アミノ酸配列：Met 1-Tyr 640
- 遺伝子構造：A DNA sequence encoding the extracellular domain of mouse LILRB3 (AAC53219.1) (Met 1-Tyr 640), was fused with a C-terminal polyhistidine tag.
- 別名（遺伝子名）：Gp91;Pirb
- 分子量：70 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-38627-Elabscience-PKSM040497.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7810-49
Recombinant Mouse LILRB3/LIR3/ILT5/CD85a Protein (His Tag) 50ug
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89-7810-50
Recombinant Mouse LILRB3/LIR3/ILT5/CD85a Protein (His Tag) 100ug
|
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