89-7810-21 ［取扱停止］Recombinant Mouse DOPA Decarboxylase/DDC Protein (His Tag) 20ug PKSM040483
[Elabscience]
特徴
- 背景：Dopa Decarboxylase (DDC), also known as AADC and Aromatic-L-amino acid decarboxylase, is a 54 kDa member of the group II decarboxylase family of proteins.It is a vitamin B6-dependent homodimeric enzyme that catalyzes the decarboxylation of both L-3,4-dihydroxyphenylalanine (L-DOPA) and L-5-hydroxytryptophan to dopamine and serotonin, respectively, which are major mammalian neurotransmitters and hormones belonging to catecholamines and indoleamines. Since L-DOPA is regularly used to treat the symptoms of Parkinson's disease, the catalytic pathway is of particular research interest. Defects of DDC are associated with severe developmental delay, oculogyric crises (OGC), as well as autosomal recessive disorder AADC deficiency, an early onset inborn error in neurotransmitter metabolism which can lead to catecholamine and serotonin deficiency.
仕様
- サイズ：20ug
- 種由来：Mouse
- 発現宿主：Baculovirus-Insect Cells
- 純度：> 90 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションＮｏ．：O88533
- タグ種類：C-His
- アミノ酸配列：Met 1-Glu 480
- 遺伝子構造：A DNA sequence encoding the mouse DDC (O88533) (Met 1-Glu 480) was expressed，with a C-terminal polyhistidine tag.
- 別名（遺伝子名）：Aadc
- 分子量：55.2 kDa
- 組成：Lyophilized from sterile 50mM Tris, 100mM NaCl, pH 8.0, 20% gly, 3mM DTT
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-38616-Elabscience-PKSM040483.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7810-22
Recombinant Mouse DOPA Decarboxylase/DDC Protein (His Tag) 100ug
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89-7810-21
Recombinant Mouse DOPA Decarboxylase/DDC Protein (His Tag) 20ug
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