89-7809-38 ［取扱停止］Recombinant Mouse Apolipoprotein A-I/ApoAI Protein (Fc Tag)(Active) 100ug PKSM040440
[Elabscience]
特徴
- 背景：Apolipoprotein A1 (APOA1) is a member of the apolipoprotein family whose members are proteins bind with lipids and form lipoproteins to translate these oil-soluble lipids such as fat and cholesterol through lymphatic and circulatory system. APOA1 is the main component of high density lipoprotein (HDL) in plasma and is involved in the esterification of cholesterol as a cofactor of lecithin-cholesterol acyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters, and thus play a major role in cholesterol efflux from peripheral cells. As a major component of the HDL complex, APOA1 helps to clear cholesterol from arteries. APOA1 is also characterized as a prostacyclin stabilizing factor, and thus may have an anticlotting effect. Defects in encoding gene may result in HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Men carrying a mutation may develop premature coronary artery disease.
仕様
- サイズ：100ug
- 種由来：Mouse
- 発現宿主：HEK293 Cells
- 純度：> 90 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションＮｏ．：Q00623
- タグ種類：C-Fc
- アミノ酸配列：Met 1-Gln 264
- 遺伝子構造：A DNA sequence encoding the mouse APOA1 (Q00623) (Met 1-Gln 264) was fused with the Fc region of human IgG1 at the C-terminus.
- 活性：1. Measured by its binding ability in a functional ELISA.2. Immobilized mouse ApoAI at 10 μg/mL (100 μl/well) can bind biotinylated human SCARB1, The EC50 of biotinylated human SCARB1 is 0.27 μg/mL.
- 別名（遺伝子名）：1-Sep;2-Sep;42248;42249;Alp-1;apo-AI;Apoa-1;apoA-I;Brp-14;Ltw-1;Lvtw-1
- 分子量：55.8 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-38591-Elabscience-PKSM040440.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7809-38
Recombinant Mouse Apolipoprotein A-I/ApoAI Protein (Fc Tag)(Active) 100ug
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89-7809-39
Recombinant Mouse Apolipoprotein A-I/ApoAI Protein (Fc Tag)(Active) 200ug
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