89-7809-24 ［取扱停止］Recombinant Mouse CHI3L1/YKL40 Protein (His Tag) 50ug PKSM040433
[Elabscience]
特徴
- 背景：Chitinase-3-like protein 1 (CHI3L1) is a secreted heparin-binding glycoprotein whose expression is associated with vascular smooth muscle cell migration. CHI3L1 is expressed at high levels in postconfluent nodular VSMC cultures and at low levels in subconfluent proliferating cultures. CHI3L1 is a tissue-restricted, chitin-binding lectin and member of glycosyl hydrolase family 18. In contrast to many other monocyto / macrophage markers, its expression is absent in monocytes and strong induced during late stages of human macrophage differentiation. Elevated levels of CHI3L1 are associated with disorders exhibiting increased connective tissue turnover, such as rheum atoid, arthritis, osteoarthritis, scleroderma, and cirrhosis of liver, but is produced in cartilage from old donors or patiens with osteoarthritis. CHI3L1 is abnormally expressed in the hippocampus of subjects with schizophrenia and may be involved in the cellular response to various environmental events that are reported to increase the risk of schizophrenia.
仕様
- サイズ：50ug
- 種由来：Mouse
- 発現宿主：HEK293 Cells
- 純度：> 97 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションＮｏ．：Q61362
- タグ種類：C-His
- アミノ酸配列：Met 1-Ala 381
- 遺伝子構造：A DNA sequence encoding the extracellular domain of mouse CHI3L1 (Q61362) (Met 1-Ala 381) was expressed, with a C-terminal polyhistidine tag.
- 別名（遺伝子名）：AW208766;Brp39;Gp39
- 分子量：42.3 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-38588-Elabscience-PKSM040433.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7809-25
Recombinant Mouse CHI3L1/YKL40 Protein (His Tag) 100ug
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89-7809-24
Recombinant Mouse CHI3L1/YKL40 Protein (His Tag) 50ug
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