89-7808-40 ［取扱停止］Recombinant Mouse TSLP Protein (His Tag)(Active) 10ug PKSM040390
[Elabscience]
特徴
- 背景：Thymic stromal lymphopoietin (TSLP) is an interleukin 7 (IL-7)-like cytokine originally characterized by its ability to promote the activation of B cells and dendritic cells (DCs). Thymic stromal lymphopoietin (TSLP) is a cytokine expressed by epithelial cells, including keratinocytes, and is important in allergic inflammation. Subsequent studies have shown that TSLP promotes T helper type 2 (TH2) cell responses associated with immunity to some helminth parasites and the pathogenesis of many inflammatory diseases, including atopic dermatitis and asthma. TSLP can promote TH2 cytokine-associated inflammation by directly promoting the effector functions of CD4+ TH2 cells, basophils and other granulocyte populations while simultaneously limiting the expression of DC-derived proinflammatory cytokines and promoting regulatory T cell responses in peripheral tissues.
仕様
- サイズ：10ug
- 種由来：Mouse
- 発現宿主：HEK293 Cells
- 純度：> 90 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションＮｏ．：Q9JIE6
- タグ種類：C-His
- アミノ酸配列：Met 1-Glu 140
- 遺伝子構造：A DNA sequence encoding the mouse TSLP (Q9JIE6) (Met 1-Glu 140) was expressed, with a C-terminal polyhistidine tag.
- 活性：Measured by its ability to bind human IL7RA-his in functional ELISA.
- 別名（遺伝子名）：Thymic stromal lymphopoietin;Thymic stroma-derived lymphopoietin;Tslp;TSLP
- 分子量：15.4 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-38558-Elabscience-PKSM040390.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7808-39
Recombinant Mouse TSLP Protein (His Tag)(Active) 5ug
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89-7808-40
Recombinant Mouse TSLP Protein (His Tag)(Active) 10ug
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