89-7808-07 ［取扱停止］Recombinant Mouse OBCAM/OPCML Protein (aa 5-313, His Tag)(Active) 50ug PKSM040373
[Elabscience]
特徴
- 背景：Opioid-binding Cell Adhesion Molecule (OBCAM), also known as OPCML, is a GPI-anchored cell adhesion molecule in the plasma membrane. This neuron-specific protein, consists of three immunoglobulin (Ig)-like domains anchored to the membrane through a glycosylphosphatidylinositol (GPI)-tail. OPCML also belongs to the member of the IgLON family, a subgroup of the immunoglobulin superfamily, consisting of three members, LAMP, OBCAM, and Neurotrimin. These molecules interact homophilically and heterophilically within the family, and OBCAM acts only as heterodimers with LAMP or Neurotrimin and possibly inhibits neurite outgrowth from cerebellar granule cells. OBCAM has been presumed to play a role as a cell adhesion/recognition molecule. Furthermore, the OPCML protein defects may play an important role in the carcinogenesis of cervical or ovarian cancers, and this gene is regarded as a candidate TSG (tumor suppressor gene).
仕様
- サイズ：50ug
- 種由来：Mouse
- 発現宿主：HEK293 Cells
- 純度：> 95 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションＮｏ．：NP_808574.2
- タグ種類：C-His
- アミノ酸配列：Ala5-Val313
- 遺伝子構造：A DNA sequence encoding the mouse OPCML (NP_808574.2) (Ala5-Val313) was expressed with a C-terminal polyhistidine tag.
- 活性：1. Measured by its binding ability in a functional ELISA.2. Immobilized mouse OPCmL-His at 10μg/mL (100μL/well) can bind human LSAMP-Fc .The EC50 of human LSAMP-Fc is 0.04-0.1 μg/mL.
- 別名（遺伝子名）：2900075O15Rik;3732419F12;AI844366;B930023M13Rik;C230027C17;Gm181;Obcam;B-CAM;Gplu;Lu
- 分子量：32.7 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-38547-Elabscience-PKSM040373.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7808-07
Recombinant Mouse OBCAM/OPCML Protein (aa 5-313, His Tag)(Active) 50ug
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89-7808-08
Recombinant Mouse OBCAM/OPCML Protein (aa 5-313, His Tag)(Active) 100ug
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