89-7808-01 ［取扱停止］Recombinant Mouse Tie2/CD202b Protein (His Tag)(Active) 100ug PKSM040370
[Elabscience]
特徴
- 背景：TEK, or TIE-2, is an endothelial cell-specific receptor tyrosine kinase (RTK) that is known as a functioning molecule of vascular endothelial cells. TEK comprises a subfamily of RTK with TIE, and these two receptors play critical roles in vascular maturation, maintenance of integrity and remodeling. Targeted mutagenesis of both Tek and its agonistic ligand, Angiopoietin-1, result in embryonic lethality, demonstrating that the signal transduction pathways mediated by this receptor are crucial for normal embryonic development. TEK signaling is indispensable for the development of the embryonic vasculature and suggests that TEK signaling may also be required for the development of the tumor vasculature.
仕様
- サイズ：100ug
- 種由来：Mouse
- 発現宿主：HEK293 Cells
- 純度：> 95 % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションＮｏ．：Q02858
- タグ種類：C-His
- アミノ酸配列：Met1-Lys744
- 遺伝子構造：A DNA sequence encoding the mouse TEK (Q02858) (Met1-Lys744) was expressed with a C-terminal polyhistidine tag.
- 活性：Measured by its binding ability in a functional ELISA.Immobilized mouse TEK-His at 10 μg/ml (100 μl/well) can bind human Ang2-Fc with a linear range of 6.25-200 ng/ml.
- 別名（遺伝子名）：AA517024;Cd202b;Hyk;STK1;Tie-2;Tie2
- 分子量：82.4 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-38544-Elabscience-PKSM040370.pdf
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商品のバリエーション （サイズ違い・スペック違い・オプション品など）
| 商品イメージ | アズワン品番 商品名 |
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89-7808-01
Recombinant Mouse Tie2/CD202b Protein (His Tag)(Active) 100ug
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89-7808-02
Recombinant Mouse Tie2/CD202b Protein (His Tag)(Active) 200ug
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