89-7807-55 Recombinant Mouse IGFBP-2/IGFBP2 Protein (Fc Tag) 100ug PKSM040345
[Elabscience]
特徴
- 背景：IGFBP-2, also known as IGFBP2, is a insulin-like growth factor-binding protein (IGFBP). IGFBPs prolong the half-life of the IGFs , control bioavailability, activity, and distribution of insulin-like growth factor (IGF) through high-affinity IGFBP/IGF complexes. Six high-affinity IGF-binding proteins (IGFBP-1 to -6) have been identified. The six IGFBPs are structurally related but encoded by distinct genes. IGFBPs have a high affinity for IGFs. Some members of the IGFBP family have been consistently shown to inhibit IGF actions by preventing them from gaining access to the IGF receptors, while others potentiate IGF actions by facilitating the ligand-receptor interaction. IGFBP-2 is overexpressed in many malignancies and is often correlated with an increasingly malignant status of the tumor, pointing to a potential involvement of IGFBP-2 in tumorigenesis. It contains 1 IGFBP N-terminal domain and 1 thyroglobulin type-1 domain. It inhibits IGF-mediated growth and developmental rates.
仕様
- サイズ：100ug
- 種由来：Mouse
- 発現宿主：HEK293 Cells
- 純度：> (65.9+24.5) % as determined by SDS-PAGE
- エンドトキシン濃度：< 1.0 EU per μg of the protein as determined by the LAL method.
- アクセッションＮｏ．：NP_032368.2
- タグ種類：C-Fc
- アミノ酸配列：Met1-Gln305
- 遺伝子構造：A DNA sequence encoding the mouse Igfbp2 (NP_032368.2) (Met1-Gln305) was expressed with the Fc region of human IgG1 at the C-terminus.
- 別名（遺伝子名）：AI255832;IBP-2;Igfbp-2;mIGFBP-2
- 分子量：56.6 kDa
- 組成：Lyophilized from sterile PBS, pH 7.4
- 保存条件：Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
- メーカーマニュアルリンク：https://www.elabscience.com/viewpdf-38526-Elabscience-PKSM040345.pdf
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| 商品イメージ | アズワン品番 商品名 |
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89-7807-55
Recombinant Mouse IGFBP-2/IGFBP2 Protein (Fc Tag) 100ug
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89-7807-54
Recombinant Mouse IGFBP-2/IGFBP2 Protein (Fc Tag) 20ug
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